22-Feb-2012 - Vital Signs: In Sinusitis, Antibiotics Are as Effective as Placebos, Study Finds

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Scientists randomized 166 adults, all of whom met the diagnostic criteria mlb jerseys from china for sinusitis, to receive the antibiotic amoxicillin or a placebo three times a day for 10 days. On the third, seventh and tenth days, the participants recorded their symptoms. There was no significant difference between the two groups in the amounts of time missed from work or everyday activities, relapse or recurrence rates, adverse effects or satisfaction with the treatment. Nor was there any difference in self-reported improvement in symptoms, except on the seventh day, when 74 percent of those taking amoxicillin reported improvement, compared with 56 percent of those on the placebo. The authors acknowledge that it is possible that nhl jerseys from china not all patients in the study had bacterial sinusitis, since the diagnosis is made clinically, not by a laboratory test. (Antibiotics, of course, are ineffective against a viral infection.) “I hope that the results here will give doctors evidence to use in discussions with patients about avoiding unnecessary antibiotic treatment,” said the lead author, nfl jerseys cheap Dr. Jane M. Garbutt of Washington University in St. Louis. The study appeared last week in The Journal of the American Medical Association.

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